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Medicadermis | Skin Therapy The Hague

Rosacea is a chronic skin condition that can manifest itself in various ways. in redness, visible blood vessels, a burning sensation and small Inflammation in the face. One of the most striking inhabitants of the skin. that regularly recurs in research into rosacea is the Demodex mite.

That does not mean that this small skin mite is the sole cause of rosacea. After all, Demodex is also present on the skin of people without rosacea. However, higher numbers are regularly found in people with rosacea. The question is therefore primarily what role Demodex plays within the much larger interplay of inflammation, immunity, blood vessels, skin barrier and microorganisms on the skin.

Briefly summarized: Demodex is a normal inhabitant of human skin. An increased amount is found in research associated with rosacea, but that doesn't mean that everyone has Demodex rosacea or that the mite is the sole cause of rosacea.

Do you suffer from rosacea, redness, or easily irritated skin yourself?

During an initial consultation, I will examine your skin and we will discuss which symptoms are most prominent for you and which approach to them can fit.

The two Demodex brothers: folliculorum and brevis

Two Demodex species occur on human skin: Demodex folliculorum and Demodex brevis. They are closely related, but do not live in exactly the same place.

Demodex folliculorum lives primarily in the hair follicles and is found, among other places, on the face and around the eyelashes. Demodex brevis lives deeper and is primarily associated with sebaceous glands.

Higher densities of Demodex are regularly found in people with rosacea. found. Researchers are therefore studying how the presence of these mites, and possibly also microorganisms associated with the mites, can influence the inflammatory responses of the skin.

Does Demodex cause rosacea?

That is probably thinking too simply. The role of Demodex in rosacea is still the subject of research. Studies show a link between a higher density of Demodex mites and rosacea, but a connection is not the same as a direct cause.

There are several possible explanations. A larger amount Demodex could exacerbate inflammatory processes in the skin. Conversely, it is also possible that changes in the skin with rosacea create an environment in which Demodex can multiply more easily. Both processes may possibly take place simultaneously.

That also fits the current view of rosacea as a condition in which not a single cause is central.The innate immune system, the blood vessels, sensory nerves, skin barrier, environmental factors and Microorganisms on the skin appear to influence each other.

Demodex around the eyes

Demodex can also occur around the eyelashes and eyelid margins. An increased presence of Demodex is associated with Demodex blepharitis, an inflammation of the eyelid margin.

Symptoms may include, among other things, irritated or itchy eyelid margins, a burning sensation, and discomfort around the eyes. In addition, other eye problems can occur with rosacea, including dry eyes and problems with the meibomian glands.

The meibomian glands are located in the eyelids and produce an oily substance. component of the tear film. When these glands do not function properly, the tear film can evaporate more quickly and dry eye symptoms may develop.

Lotilaner for Demodex blepharitis

An interesting development is lotilaner ophthalmic solution 0.25%. Research has shown that Lotilaner can be effective for Demodex blepharitis. In the United States, the drug was in Approved by the FDA in 2023 under the brand name Xdemvy for the treatment of Demodex blepharitis.

Lotilaner belongs to a group of substances that work against parasites. The active ingredient is interesting because Demodex is a mite and therefore not bacteria

This concerns a pharmacological treatment of Demodex blepharitis. This is something different than the dermatological treatment of rosacea or dry eyes and belongs within the designated medical eye care.

Tea tree oil for Demodex?

Anyone searching the internet for ways to combat Demodex, You quickly come across tea tree oil. However, for a sensitive person, I would... Do not just experiment with rosacea-prone skin on your own.

Tea tree oil contains biologically active substances and can harm the skin and eyes. irritate. Especially with rosacea, the skin barrier can already be fragile and stimuli can be experienced much more strongly.

The same applies to an increasingly extensive skincare routine. More products do not automatically mean better rosacea skin. Sometimes it is actually wise to simplify the routine and first to see which products the skin actually tolerates.

Treating rosacea: looking beyond Demodex

Because Demodex is only one part of the story, a focuses Rosacea treatment does not automatically focus on combating the mite. First, it must become clear which characteristics of your skin on the to stand in the foreground.

In one person, these are mainly inflammations and a sensitive skin barrier. In someone else, it is actually diffuse redness and superficial blood vessels. Yet another person also has complaints of the eyelids or dry eyes.

Therefore, in my practice, I look at the skin as a whole: redness, capillaries, inflammation, sensitivity, skin barrier, skin care, medication, sun exposure and possible triggering factors.

IPL and rosacea

When especially redness and superficial blood vessels If it takes center stage, IPL can be part of the treatment plan. At Medicademis, I work with the for this. Lumenis M22.

The light from IPL can be absorbed by hemoglobin in the blood. The heat generated in the process can be used to superficial to treat vascular structures in a targeted manner. The goal is a reduction of visible blood vessels and redness.

IPL is therefore not a treatment that simply removes Demodex from the skin. removes it, and it does not eliminate the predisposition to rosacea either. It deals with certain visible characteristics of rosacea.

Whether IPL is suitable depends on, among other things, the skin type, the vascular component, the current condition of the skin, medication and sun exposure. That is why I assess the skin beforehand.

Rosacea, Demodex, redness, dry eyes: where do you start?

You don't have to figure out which treatment you need yourself first. During an introductory meeting, we can look at which complaints you have. stand in the foreground and what the logical next step is.

What can you do yourself for rosacea?

With rosacea, it is often more sensible to keep the skin as stable as possible. then keep it to try to aggressively combat Demodex at home.

A simple skincare routine, gentle cleansing, support of the skin barrier and daily protection against UV radiation often forms an important starting point.

Additionally, it can be useful to recognize what your skin reacts to. Heat, sunlight, temperature fluctuations, certain cosmetics, alcohol and spicy food, for example, can affect some people. trigger flushing or redness. Which factors are important, However, it varies greatly from person to person.

If you use many different products, feel free to bring them along. to practice. I look at it from the perspective of my knowledge of cosmetic ingredients and skincare with you regarding what you use and whether the combination suits the condition of your skin.

The core: Demodex is an interesting part of the rosacea research, but rosacea is much more complex than just a 'skin mite problem'. A good treatment therefore focuses on the characteristics and needs of your skin as a whole.

Do you want to know what suits your rosacea?

You are welcome at Medikadermis in The Hague for a free first session. introduction.If you would like to consult remotely first, you can also a Schedule a free video consultation.

Literature and scientific sources used
  • Du J, Gao R, Zhao J. (2021). The Effect of Volatile Oil from Chinese Mugwort Leaf on Human Demodecid Mites In Vitro. Acta Parasitologica, 66(2), 615–622.
  • Forton FMN. (2020). The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea? Dermatology and Therapy, 10(6), 1229–1253.
  • Smith G, Manzano-Marín A, Reyes-Prieto M, et al. (2022). Human Follicular Mites: Ectoparasites Becoming Symbionts. Molecular Biology and Evolution, 39(6), msac125.
  • Yeu E, Wirta DL, Karpecki P, Baba SN, Holdbrook M. (2023). Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis: Results of a Prospective, Randomized, Vehicle-Controlled, Double-Masked, Pivotal Trial (Saturn-1). Cornea, 42(4), 435–443.
  • Zamecnik A. (2023). FDA approves first-ever therapy for Demodex blepharitis. GlobalData's Pharma Intelligence Center.

About the author

Charlotte de Deugd is a skin therapist and owner of Medicadermis in The Hague. In her practice, she treats including rosacea, redness, visible blood vessels, acne, pigmentation problems, scars and edema.

With rosacea, she looks not only at visible redness, but also at the condition of the skin barrier, vascular component, inflammatory activity, skincare and possible triggering factors.

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