Music of the future from the crystal ball of Medicadermis
The skin care market in the Netherlands is growing modestly. In 2023, the market is estimated at around 890 million euros, with an expected annual growth of just over 3% in the coming years. Globally, it is growing at a slightly stronger pace of 6.0% until 2032. The increasing popularity of cosmeceuticals (combination of cosmetics and pharmaceuticals) is driving demand. Especially among younger consumers who are increasingly interested in premium skin care products. But in general, growth is driven by an increasing awareness of skin health, the increasing aging of the population and the growing demand for anti-aging and self-care products.
The demand for natural, organic and herbal ingredients is also shifting. These products are gaining popularity due to their safety and effectiveness. Innovations in product formulations and the rise of online sales channels are contributing to further growth. Advances in technology, such as nano-particle delivery systems and personalized skin care solutions, are expected to improve performance and thus customer satisfaction.
Boring? Maybe! But things are moving fast. So we want, no, we need to know what awaits us as "skins". Now, and in the near future.
Sun's a bitch
The holy grail of skincare is skin rejuvenation. Scientists are constantly looking for the next breakthrough for youthful, radiant skin. Recently, Nicotinamide Mononucleotide (NMN) has been discovered as a potential game-changer in the fight against skin aging. In which the sun, as is well known, plays a leading role. NMN, already known for the improving cellular energy, is now being studied for its benefits in skin care. In particular, our resistance to UV-B influence on the skin. A study of this has been published in the journal Nature.
What is NMN?
NMN is a naturally occurring molecule in our bodies that plays a crucial role in the production of Nicotinamide Adenine Dinucleotide (NAD+). This is a coenzyme with an essential function in cell metabolism (including DNA repair and energy production). As we age, the levels of NAD+ in our bodies decrease, leading to several signs of aging. Such as decreased skin elasticity and increased wrinkles. By supplementing NMN, researchers hope to restore NAD+ levels, promoting healthier, more youthful skin.
NMN and Skin Health
The results of a study conducted by researchers at Tokushima University in Japan are promising. NMN has the potential to combat skin aging. The study combines NMN with the probiotic Lactobacillus fermentum TKSN041. This combination protects the skin from UVB induced damage, a major cause by premature aging. The study opted for gastric administration, but due to the high water solubility of NMN, the study encountered challenges in penetrating the skin barrier.
To solve this problem To solve this, the researchers have developed a special nanoparticle delivery system that effectively allows NMN to penetrate human skin cells. This is currently being tested on the ability to suppress cell aging, activate cell division, improve energy production and increase hyaluronic acid production. Hyaluronic acid has the ability to retain moisture, improve skin elasticity and give a full, youthful appearance.
The Way Forward
Although initial findings are promising, more research is needed to fully understand the effects of NMN on human skin.To date, studies have been conducted on a small scale and larger clinical trials are needed to determine the optimal dosing and long-term safety of NMN in skin care. In addition, the interaction between NMN and the gut microbiome needs to be further investigated to optimize absorption and efficacy when taken orally.
Conclusion
The potential of NMN to revolutionize skin care is undeniable. As research continues, we may soon see NMN-based products that effectively combat the signs of aging. They offer a new, scientifically proven solution to maintaining youthful, radiant skin. For those who like up to date want to stay about skin care innovation it is interesting to continue to follow developments in NMN research.
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