Lira Clinical PRO C4 Retinol Serum

For which skin type is the PRO C4 Retinol Serum suitable?

This serum can fit into a skincare routine for:

• fine lines and signs of skin aging;
• a coarse or uneven skin texture;
• pigment spots and sun damage;
• a dull or uneven complexion;
• impurities and residual spots after acne;
• a thickened or irregular stratum corneum.

Extra caution is required for sensitive, dry, or easily reddened skin. In such cases, it must first be assessed whether the skin barrier is sufficiently calm and stable for the use of retinol.

What does the PRO C4 Retinol Serum do?

The formula combines active skincare with hydrating and antioxidant ingredients.

• Retinol 1% supports normal cell renewal and can help to gradually improve skin texture, fine lines, and impurities.
• Vitamin C complex 20% Consists of Tetrahexyldecyl Ascorbate, Ascorbyl Palmitate, Ascorbic Acid, and Citric Acid. Vitamin C acts as an antioxidant and supports collagen formation and a more even complexion.
• Hyaluronic acid helps retain moisture in the skin and supports a supple and comfortable skin feel.
• Licorice extract has nourishing and soothing properties and can contribute to a more even complexion.
• Green tea, vitamin E, ubiquinone and olive leaf extract support the antioxidant effect of the formula.
• Botanical cell culture extracts Ingredients including apple, sea fennel, edelweiss, and alpine rose are added to the formula as skin-care ingredients.

Alignment with Medicadermis treatment programs

• LIFT – focused on skin structure, firmness, and signs of skin aging.
• SPOT – targeting pigment spots and an uneven complexion.
• EVEN – focused on skin texture, imperfections, and residual spots.
• SHINE – targeted at impurities and clearer skin.
• RED – in case of redness or sensitivity, retinol is used only cautiously and after assessment.

How do you use the PRO C4 Retinol Serum?

1. Cleanse the skin with a mild cleanser.
2. Let the skin dry completely.
3. Apply one pump thinly to the face and, if desired, the neck.
4. Avoid the eyelids, corners of the mouth, and irritated skin.
5. Then apply a suitable moisturizing cream.
6. Always use broad-spectrum sun protection during the day.

Gradually build up retinol

Preferably start with two evenings per week. If the skin tolerates this well, the frequency can be gradually increased. Using more product or more often does not automatically yield better results, but it does increase the risk of irritation.

Dryness, flaking, or mild sensitivity may occur during the build-up phase. Temporarily discontinue use if the skin feels clearly burning, intensely red, or damaged.

Around skin treatments

Do not use this serum without coordination around peels, microneedling, IPL, laser treatments, or other intensive skin treatments. Retinol must be temporarily discontinued prior to some treatments and only reintroduced after sufficient skin recovery.

Complete list of ingredients

WATER (AQUA), TETRAHEXYLDECYL ASCORBATE, GLYCERIN, DIMETHICONE, CETEARYL OLIVATE, SORBITAN OLIVATE, SODIUM HYALURONATE CROSSPOLYMER, CETYL PALMITATE, SORBITAN PALMITATE, MALUS DOMESTICA FRUIT CELL CULTURE, LECITHIN, IMPERATA CYLINDRICA ROOT EXTRACT, PHENOXYETHANOL, CAPRYLYL GLYCOL, ETHYLHEXYLGLYCERIN, HEXYLENE GLYCOL, BUTYLENE GLYCOL, YEAST POLYSACCHARIDES, PPG-12/SMDI COPOLYMER, CETEARYL ALCOHOL, RETINOL, POLYSORBATE 20, CAMELLIA SINENSIS LEAF EXTRACT, BETA VULGARIAN (BEET) ROOT EXTRACT, HABERLEA RHODOPENSIS LEAF EXTRACT, YEAST EXTRACT, TOCOPHEROL, ASCORBYL PALMITATE, ASCORBIC ACID, CITRIC ACID, CULTURE, RHODODENDRON FERRUGINEUM LEAF CELL CULTURE EXTRACT, ISOMALT, LACTIC ACID, DISODIUM EDTA, ALOE BARBADENSIS LEAF JUICE POWDER, UBIQUINONE, OLEA EUROPAEA (OLIVE) LEAF EXTRACT, CITRUS AURANTIUM DULCIS (ORANGE) PEEL OIL.

Why is a gradual build-up important?

Retinol is a powerful ingredient. Starting too soon or too often can lead to dryness, redness, flaking, and irritation. Therefore, when I have questions, I look not only at the product but also at your skin condition, current routine, previous reactions, and any skin treatments.

The PRO C4 Retinol Serum can be used for skin aging, pigmentation spots, acne residue, and sun damage. Whether this serum is suitable for your skin depends on the current condition and resilience of the skin.

Are you curious about the price or would you like to order the serum? Feel free to send me a WhatsApp, call me, or fill out the contact form. Your order can be shipped throughout the Netherlands or picked up by appointment at my practice in The Hague.

Can I use this retinol serum every evening?

Not immediately. Start with two evenings a week and only increase usage when your skin tolerates the serum well.

Can I use the serum on sensitive skin?

That depends on the condition of your skin barrier.For active redness, irritation, eczema, or damaged skin, retinol is usually not the first step.

Can I combine retinol with vitamin C?

This serum itself contains various forms of vitamin C. It is not without reason that multiple strong active products are added. The entire routine must be sufficiently tolerated by the skin.

Can I use this product around a peel or laser treatment?

Only after consultation. Retinol must be temporarily stopped around some treatments. The right time to start again depends on the type of treatment and your skin's recovery.

Should I use sun protection?

Yes. Daily sun protection is essential within a skincare routine with retinol, especially when you want to address pigmentation spots or sun damage.

Retinoids are among the extensively researched ingredients in dermatological skincare. In the literature, they are described in relation to cell renewal, collagen-related processes, skin structure, and signs of skin aging.

Vitamin C is an antioxidant and plays a role in collagen formation and protection against oxidative stress. Its efficacy within a cosmetic formula depends, among other things, on the form used, the concentration, stability, and formulation.

Background literature: Mukherjee et al. (2006), on retinoids in skin aging, and Pullar et al. (2017), on the role of vitamin C in skin health.

Read also: retinol and skin improvement at Medicadermis in The Hague.